AN IMPORTANT MESSAGE FROM CONCERNED STOCKHOLDERS OF UPHEALTH, INC. TO THEIR FELLOW STOCKHOLDERS

Dear Fellow UpHealth, Inc. Stockholder:

You will soon receive or may have already received a proxy statement and accompanying white proxy card from UpHealth, Inc. (the “Company”) in connection with the upcoming 2022 Annual Meeting of Stockholders of the Company (the “Annual Meeting”), set for 9:00 a.m., Pacific Time, on Tuesday, June 28, 2022. The meetin…